18 months Postdoctoral Position in Chromatography and Antibody-Drug-Conjugates (ADCs)

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Symphogen, the Antibody Center of Excellence within the Servier Group, is dedicated to developing antibody-based therapeutic products for treating cancer and neuroinflammatory diseases. Our Analytical Development team plays a crucial role in advancing our targets through lead selection, clinical development, and commercialization.

We are strengthening our capabilities in process development of conjugation reactions and subsequent analysis of conjugated material of Antibody-Drug Conjugates (ADCs) and seeking a scientist or similar professional for a postdoctoral position within our Analytical development team in close collaboration with the Drug Substance Development department. Our state-of-the-art laboratory is equipped to handle all aspects of protein testing, including (U)HPLCs, MS, iCIEF, CE-SDS, MFI, CD, ELISA, DSC, DLS, and MALS. The department comprises 20 scientists and technicians specializing in protein analysis to support method development, troubleshooting, process development, validation, stability studies, and more, in collaboration with colleagues from other departments within Symphogen, Servier, and at CMOs.

This position offers a unique opportunity to be part of a dedicated scientific team working in an innovative and important area, focusing on the analysis and conjugation chemistry of linker/payload and antibodies.

The ideal candidate for this position has:

  • 2-3 years of experience in protein chemistry
  • A Ph.D. degree within protein chemistry, analysis or similar.
  • Profound experience with HPLC, preferably within 2d-HPLC.
  • Experience with analytical techniques such as SEC, CIEX, RPC, HIC, and HILIC
  • Hands-on laboratory experience in general, and specifically, with different kinds of conjugation chemistry.
  • Familiarity with other protein analysis techniques like CE, MS, or biophysical methods

As a person, you are self-driven, pragmatic, and capable of working effectively in teams. A commitment to your work, a scientific curiosity, a proactive attitude, and a sense of humor are also essential qualities.

Working at Symphogen: Symphogen offers a challenging job in a creative, goal-oriented, and value-based environment with a meaningful mission: to advance superior next-generation antibody therapeutics to improve patients’ lives. You will be part of a highly engaged and inspiring organization that values diversity, teamwork, and commitment. We offer good development opportunities and a relevant benefits package.

Duration: This is a 1½-year temporary position with the possibility of an additional 1½-year extension. Expected start date as soon as possible.

Traveling: Limited, up to ten days per year.

For further information about the position, please contact Senior Scientist Karsten Hartvigsen at +45 4252 8410 (kaha@symphogen.com) or Team Manager Christian Glue at +45 2194 7517 (cglu@symphogen.com), or HR-Manager at +45 4526 5050.

If you are interested in applying for the position, please mark your application and CV with “Postdoc, ADC development” and send it to job@symphogen.com no later than October 27th, 2024. Potential candidates will be invited for interviews as they apply, and we reserve the right to close the posting before the deadline.

Company

Symphogen is a subsidiary of Servier and antibody center of excellence primarily focused on oncology and immune oncology. We have a highly efficient antibody discovery and research platform supported by comprehensive early development capabilities.

Our antibody platform delivers antibodies with unique functionalities providing best or first in class potential as combination or mono therapy. Our approach and capabilities are well suited for combination therapies at the core of future cancer treatment.

Symphogen is located in Ballerup in the greater Copenhagen area. The company currently employs approximately 150 people

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