Senior/Principal Scientist, Cell Biology and Screening

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About Symphogen

Symphogen has entered an exciting phase as the Antibody Center of Excellence in Servier with a continued focus on the discovery and early development of novel antibody-based therapeutic products for the treatment of cancer and inflammatory diseases.

Job description

We are looking for an experienced and motivated Senior/Principal Scientist to join the Cell Biology and Screening department. You will be responsible for designing and analyzing in vitro experiments to support the advancement of our antibody-based pre-clinical programs.

Your main tasks are (but are not limited to):

  • Lead the design, development and implementation of assays needed for functional screening and characterization of antibody repertoires and lead candidates within the areas of cancer biology, immune-oncology, and inflammation.
  • Be part of cross-functional project teams and collaborate closely with other departments to advance our drug discovery projects from target identification to early clinical development.
  • Stay abreast of scientific literature and emerging trends and contribute to the evaluation and implementation of new methodologies and technologies.
  • Responsible for planning daily work activities in collaboration with laboratory technicians.
  • Analyze and interpret experimental data, prepare documentation, and present findings to stakeholders at Symphogen and Servier.

Qualifications

To thrive in this role, we imagine that you have:

  • Ph.D. in cancer biology, immunology, or immuno-oncology, or a related field, and ideally 3+ years of relevant experience.
  • Solid understanding of experimental methodologies and the ability to develop target-specific assays within the field of tumor biology or immuno-oncology.
  • Experience in a wide range of molecular and cellular biology techniques such as multiparameter flow cytometry, ELISA, internalization, cytotoxicity, and apoptosis assays.
  • Proficiency in English and good presentation skills.
  • A collaborative spirit and capable of building and maintaining networks within and outside the organization.
  • Prior experience working with antibody-therapeutics (e.g., bispecifics or ADCs) and/or experience with the drug discovery process is beneficial.

On the personal level, you have an innovative and goal-oriented mindset with a commitment to meet deadlines. You have a high degree of drive and pro-activeness with the ability to adjust quickly to new tasks, and is comfortable working in a cross-functional, and complex project-based environment.

About the Cell Biology and Screening department

The Cell Biology and Screening department comprises 16 highly skilled technicians and scientists. We use state-off the art in vitro techniques and technologies to support our programs throughout the entire pre-clinical phase i.e., functional screening and characterization of lead candidates as well as mode of action studies on the final lead antibody. Our department is a part of the Biologics Drug Design (BDD) area at Symphogen, working closely together with other disciplines in R&D, such as CMC and the therapeutic areas located at the Servier headquarters in Paris.

Travelling: Limited. Approximately 10 days per year, primarily to the Servier headquarters in Paris

Domicile: Symphogen’s office in Ballerup

For more details about the job, please get in touch with team manager Anton Willer at +45 51 94 05 52, anwi@symphogen.com or Director Trine Lindsted at +45 61 68 26 13, tli@symphogen.com. All applications must be in English and are treated confidentially.

Please submit application and CV, marked ‘Senior/Principal Scientist, Cell Biology and Screening’ by email to job@symphogen.com no later than 15 June 2024. Potential candidates will be interviewed on a rolling basis, and we reserve the right to close the position before the deadline if the right candidate is found.

Company

Symphogen is a subsidiary of Servier and antibody center of excellence primarily focused on oncology and immune oncology. We have a highly efficient antibody discovery and research platform supported by comprehensive early development capabilities.

Our antibody platform delivers antibodies with unique functionalities providing best or first in class potential as combination or mono therapy. Our approach and capabilities are well suited for combination therapies at the core of future cancer treatment.

Symphogen is located in Ballerup in the greater Copenhagen area. The company currently employs approximately 150 people

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